REPLICATING THE COMPLEX
TRUE TISSUE ON PLATFORM'S MODULAR AND VERSATILE PLATFORM enables to design and carry out highly customizable and controlled experiments, with a plug and play approach avoiding complex handling equirements.
THE
PROBLEM
It is estimated that, to put a new drug on the market, are required more than $2B and 10-12 years in R&D. More than 80% of drugs that look promising in animal models fail when tested in humans.
TToP is a modular, versatile, and user-friendly MicroPhysiolgical platform that guarantees more predictive results than conventional cell culture technologies, replicating complex human pathophysiological conditions, minimizing the controversial animal use in research.
True Tissue On Platform is based on a cartridge-based design suitable for well-established studies and for cutting-edge culture methodologies.
The patented technology enables the controlled management of the biological sample, allowing to retrieve it without damages to perform end-point analysis or to reuse it, designing sequential treatments.
THE
TECHNOLOGY
THE
PRODUCTS
TToP enables the construction of compartmental culture models, introducing a novel feature that enables easy retrieval of the biological material without damages, for end-point analysis or sequential conditioning.
The system has a cartridge-based design. In the cartridge, it is possible to host microporous polymeric membranes, or 3D structures, such as planar scaffolds or even thin tissue biopsies.
TToP versatily allow to host multiple types of biological samples.
THE
Applications
THE
PROBLEM
The drug development process is very expensive and requires very long times.
It is estimated that, to put a new drug on the market, are required more than $2B and 10-12 years in R&D. More than 80% of drugs that look promising in animal models fail when tested in humans, 60% of those failures due to a limited efficacy and another 30% due to cell/organ toxicity.
TToP is a modular, versatile, and user-friendly MicroPhysiolgical platform that guarantees more predictive results than conventional cell culture technologies, replicating complex human pathophysiological conditions, minimizing the controversial animal use in research.
TToP is a modular, versatile, and user-friendly MicroPhysiolgical platform that guarantees more predictive results than conventional cell culture technologies, replicating complex human pathophysiological conditions, minimizing the controversial animal use in research.
THE
TECHNOLOGY
TToP is based on a cartridge-based design suitable for well-established studies and for cutting-edge culture methodologies.
The patented technology enables the controlled management of the biological sample, allowing to retrieve it without damages to perform end-point analysis or to reuse it, designing sequential treatments.
The patented technology enables the controlled management of the biological sample, allowing to retrieve it without damages to perform end-point analysis or to reuse it, designing sequential treatments.
THE
PRODUCTS
TToP enables the construction of compartmental culture models, introducing a novel feature that enables easy retrieval of the biological material without damages, for end-point analysis or sequential conditioning.
The system has a cartridge-based design. In the cartridge, it is possible to host microporous polymeric membranes, or 3D structures, such as planar scaffolds or even thin tissue biopsies.
THE
Applications
TToP
versatily allow to host multiple types of biological samples.